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AZ7550 hydrochloride
CAS No. 2309762-40-9
AZ7550 hydrochloride ( AZ7550 hydrochloride (1421373-99-0 free base) )
Catalog No. M26549 CAS No. 2309762-40-9
AZ7550 hydrochloride, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 231 | Get Quote |
|
| 10MG | 357 | Get Quote |
|
| 25MG | 597 | Get Quote |
|
| 50MG | 851 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameAZ7550 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionAZ7550 hydrochloride, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
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DescriptionAZ7550 hydrochloride, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).(In Vitro):AZ7550 (Compound 28) inhibits double mutant (DM) cell line H1975, activating mutant (AM) cell line PC9, and wild type (WT) cell line LoVo (IC50s: 45, 26, and 786 nM). AZ7550 inhibits DM antiproliferative cell line H1975, AM antiproliferative cell line PC9, and WT antiproliferative cell line Calu3 (GI50s: 19, 15, and 537 nM).
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SynonymsAZ7550 hydrochloride (1421373-99-0 free base)
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PathwayAngiogenesis
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TargetEGFR
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RecptorBacterial; GABAA; Human Endogenous Metabolite; Virus Protease
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Research Area——
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Indication——
Chemical Information
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CAS Number2309762-40-9
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Formula Weight522.0
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Molecular FormulaC27H32ClN7O2
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Purity>98% (HPLC)
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Solubility——
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SMILESC=CC(NC1=CC(NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2)=C(OC)C=C1N(C)CCNC)=O.[H]Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Yang H, et al. α-Pinene, a Major Constituent of Pine Tree Oils, Enhances Non-Rapid Eye Movement Sleep in Mice through GABAA-benzodiazepine Receptors. Mol Pharmacol. 2016 Nov;90(5):530-539.
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